HBV Target gene Detail Information

> FGG Gene Search Result

Gene Information

Gene Name	FGG
Gene ID	2266
Gene Full Name	fibrinogen gamma chain
Transcripts	ENSG00000171557
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P02679
HGNC ID	HGNC:3694
VEGA ID	OTTHUMG00000150329
OMIM ID	134850
String ID	9606.ENSP00000336829
Drugbank ID	BE0002092; BE0009672
PharmGKB ID	PA430

Target gene [FGG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006133	chr4	8	17	18	43	View
1006197	chr4	7	17	18	42	View
1010081	chr4	2	10	1	13	View
1010082	chr4	2	10	1	13	View
1013592	chr4	1	4		5	View
1400182	chr4	2	11	1	14	View
1404186	chr4	6	2		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FGG expression and immune infiltrating cell level correlation result in HBV+ samples
FGG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).