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HBV Target gene Detail Information

> FGF4 Gene Search Result


Gene Information
Gene Name FGF4
Gene ID 2249
Gene Full Name fibroblast growth factor 4
Gene Alias HST; KFGF; FGF-4; HST-1; HSTF1; K-FGF; HBGF-4; HSTF-1
Transcripts ENSG00000075388
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P08620
HGNC ID HGNC:3682
VEGA ID OTTHUMG00000167887
OMIM ID 164980
String ID 9606.ENSP00000168712
Drugbank ID BE0000326
PharmGKB ID PA28121
Target gene [FGF4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001912 chr11 335 43 47 425 View
1013775 chr11 3 1 4 View
1015319 chr11 2 2 View
1401244 chr11 3 1 4 View
1401245 chr11 335 43 47 425 View
1401400 chr11 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FGF4 expression and immune infiltrating cell level correlation result in HBV+ samples
FGF4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).