HBV Target gene Detail Information

> FGF10 Gene Search Result


Gene Information
Gene Name FGF10
Gene ID 2255
Gene Full Name fibroblast growth factor 10
Transcripts ENSG00000070193
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted secreted proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID O15520
HGNC ID HGNC:3666
VEGA ID OTTHUMG00000131153
OMIM ID 602115
String ID 9606.ENSP00000264664
PharmGKB ID PA28106
Target gene [FGF10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017110 chr5 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FGF10 expression and immune infiltrating cell level correlation result in HBV+ samples
FGF10 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).