HBV Target gene Detail Information

> FGD4 Gene Search Result

Gene Information

Gene Name	FGD4
Gene ID	121512
Gene Full Name	FYVE, RhoGEF and PH domain containing 4
Gene Alias	CMT4H; FRABP; ZFYVE6
Transcripts	ENSG00000139132
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96M96
HGNC ID	HGNC:19125
VEGA ID	OTTHUMG00000137374
OMIM ID	611104
String ID	9606.ENSP00000394487
PharmGKB ID	PA134907925

Target gene [FGD4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008992	chr12	18			18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FGD4 expression and immune infiltrating cell level correlation result in HBV+ samples
FGD4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).