HIV Target gene Detail Information

> FEZ2 Gene Search Result

Gene Information

Gene Name	FEZ2
Gene ID	9637
Gene Full Name	fasciculation and elongation protein zeta 2
Gene Alias	HUM3CL
Transcripts	ENSG00000171055
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoli rim;Cytosol;Golgi apparatus;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9UHY8
HGNC ID	HGNC:3660
VEGA ID	OTTHUMG00000152148
OMIM ID	604826
String ID	9606.ENSP00000368547
PharmGKB ID	PA28101

Target gene [FEZ2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000162	chr2	591	189	69	849	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FEZ2 expression and immune infiltrating cell level correlation result in HIV+ samples
FEZ2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FEZ2 expression and immune infiltrating cell level correlation result in HIV+ samples
FEZ2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).