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HBV Target gene Detail Information

> FCHO1 Gene Search Result


Gene Information
Gene Name FCHO1
Gene ID 23149
Gene Full Name FCH domain only 1
Transcripts ENSG00000130475
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O14526
HGNC ID HGNC:29002
VEGA ID OTTHUMG00000183293
OMIM ID 613437
String ID 9606.ENSP00000473001
PharmGKB ID PA134870625
Target gene [FCHO1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001287 chr19 78 145 591 814 View
1402895 chr19 78 145 591 814 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of FCHO1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FCHO1 expression: Low -> High
Lollipop of FCHO1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of FCHO1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FCHO1 expression and immune infiltrating cell level correlation result in HBV+ samples
FCHO1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).