HIV Target gene Detail Information

> FCGRT Gene Search Result

Gene Information

Gene Name	FCGRT
Gene ID	2217
Gene Full Name	Fc fragment of IgG receptor and transporter
Gene Alias	FCRN; alpha-chain
Transcripts	ENSG00000104870
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P55899
HGNC ID	HGNC:3621
VEGA ID	OTTHUMG00000183155
OMIM ID	601437
String ID	9606.ENSP00000221466
PharmGKB ID	PA28067

Target gene [FCGRT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005510	chr19	23	1	8	32	View
4006963	chr19	15	6		21	View
4011598	chr19	6			6	View
4014733	chr19		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FCGRT expression and immune infiltrating cell level correlation result in HIV+ samples
FCGRT expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FCGRT expression and immune infiltrating cell level correlation result in HIV+ samples
FCGRT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).