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HTLV1 Target gene Detail Information

> FCER2 Gene Search Result


Gene Information
Gene Name FCER2
Gene ID 2208
Gene Full Name Fc fragment of IgE receptor II
Gene Alias CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2
Transcripts ENSG00000104921
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P06734
HGNC ID HGNC:3612
VEGA ID OTTHUMG00000182517
OMIM ID 151445
String ID 9606.ENSP00000264072
Drugbank ID BE0003465
PharmGKB ID PA28058
Target gene [FCER2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002905 chr19 29 116 55 200 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of FCER2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCER2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of FCER2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCER2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of FCER2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCER2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).