HIV Target gene Detail Information

> FBXW7 Gene Search Result

Gene Information

Gene Name	FBXW7
Gene ID	55294
Gene Full Name	F-box and WD repeat domain containing 7
Gene Alias	AGO; CDC4; FBW6; FBW7; hAgo; FBX30; FBXW6; SEL10; hCdc4; FBXO30; SEL-10
Transcripts	ENSG00000109670
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q969H0
HGNC ID	HGNC:16712
VEGA ID	OTTHUMG00000185246
OMIM ID	606278
String ID	9606.ENSP00000281708
PharmGKB ID	PA28054

Target gene [FBXW7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002351	chr4	69	4	25	98	View
4002684	chr4	21	17	46	84	View
4003317	chr4	55	7	2	64	View
4004225	chr4	35	8	4	47	View
4006977	chr4	4	13	4	21	View
4009090	chr4	13			13	View
4009478	chr4	1	10		11	View
4012319	chr4	3	2		5	View
4013326	chr4	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FBXW7 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXW7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FBXW7 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXW7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).