HIV Target gene Detail Information

> FBXO8 Gene Search Result

Gene Information

Gene Name	FBXO8
Gene ID	26269
Gene Full Name	F-box protein 8
Gene Alias	FBS; DC10; FBX8
Transcripts	ENSG00000164117
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NRD0
HGNC ID	HGNC:13587
VEGA ID	OTTHUMG00000160746
OMIM ID	605649
String ID	9606.ENSP00000377280
PharmGKB ID	PA28048

Target gene [FBXO8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008435	chr4	15			15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FBXO8 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FBXO8 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).