HIV Target gene Detail Information

> FBXO7 Gene Search Result

Gene Information

Gene Name	FBXO7
Gene ID	25793
Gene Full Name	F-box protein 7
Gene Alias	FBX; FBX7; PKPS; FBX07; PARK15
Transcripts	ENSG00000100225
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9Y3I1
HGNC ID	HGNC:13586
VEGA ID	OTTHUMG00000030674
OMIM ID	605648
String ID	9606.ENSP00000266087
PharmGKB ID	PA28047

Target gene [FBXO7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006699	chr22	20	3		23	View
4006887	chr22	19	3		22	View
4011913	chr22	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FBXO7 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FBXO7 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).