HIV Target gene Detail Information

> FBXO32 Gene Search Result

Gene Information

Gene Name	FBXO32
Gene ID	114907
Gene Full Name	F-box protein 32
Gene Alias	Fbx32; MAFbx
Transcripts	ENSG00000156804
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q969P5
HGNC ID	HGNC:16731
VEGA ID	OTTHUMG00000164981
OMIM ID	606604
String ID	9606.ENSP00000428205
PharmGKB ID	PA28043

Target gene [FBXO32] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006503	chr8	20	4		24	View
4009393	chr8	4	8		12	View
4300030	chr8	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FBXO32 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO32 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FBXO32 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXO32 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).