HBV Target gene Detail Information

> FBXO15 Gene Search Result

Gene Information

Gene Name	FBXO15
Gene ID	201456
Gene Full Name	F-box protein 15
Gene Alias	FBX15
Transcripts	ENSG00000141665
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NCQ5
HGNC ID	HGNC:13617
VEGA ID	OTTHUMG00000132842
OMIM ID	609093
String ID	9606.ENSP00000393154
PharmGKB ID	PA134894755

Target gene [FBXO15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004102	chr18	31	23	39	93	View
1004105	chr18	31	23	39	93	View
1004106	chr18	31	23	39	93	View
1016326	chr18	1			1	View
1400521	chr18	13	39	9	61	View
1402522	chr18	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of FBXO15 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FBXO15 expression: Low -> High
Lollipop of FBXO15 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of FBXO15 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FBXO15 expression and immune infiltrating cell level correlation result in HBV+ samples
FBXO15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).