HIV Target gene Detail Information

> FBXL4 Gene Search Result

Gene Information

Gene Name	FBXL4
Gene ID	26235
Gene Full Name	F-box and leucine rich repeat protein 4
Gene Alias	FBL4; FBL5; MTDPS13
Transcripts	ENSG00000112234
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UKA2
HGNC ID	HGNC:13601
VEGA ID	OTTHUMG00000015259
OMIM ID	605654
String ID	9606.ENSP00000358247
PharmGKB ID	PA28024

Target gene [FBXL4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000932	chr6	180	28	38	246	View
4002063	chr6	109	5		114	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FBXL4 expression and immune infiltrating cell level correlation result in HIV+ samples
FBXL4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).