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HTLV1 Target gene Detail Information

> FBXL16 Gene Search Result


Gene Information
Gene Name FBXL16
Gene ID 146330
Gene Full Name F-box and leucine rich repeat protein 16
Gene Alias Fbl16; C16orf22; c380A1.1
Transcripts ENSG00000127585
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N461
HGNC ID HGNC:14150
VEGA ID OTTHUMG00000090420
OMIM ID 609082
String ID 9606.ENSP00000380746
PharmGKB ID PA25536
Target gene [FBXL16] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000230 chr16 1713 761 268 2742 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of FBXL16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FBXL16 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of FBXL16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FBXL16 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of FBXL16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FBXL16 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).