HTLV1 Target gene Detail Information

> FAT1 Gene Search Result

Gene Information

Gene Name	FAT1
Gene ID	2195
Gene Full Name	FAT atypical cadherin 1
Gene Alias	FAT; ME5; CDHF7; CDHR8; hFat1
Transcripts	ENSG00000083857
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q14517
HGNC ID	HGNC:3595
VEGA ID	OTTHUMG00000160320
OMIM ID	600976
String ID	9606.ENSP00000406229
PharmGKB ID	PA164719952

Target gene [FAT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001256	chr4	275	33	204	512	View
6018788	chr4	9			9	View
6030815	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of FAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FAT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).