HIV Target gene Detail Information

> FANCI Gene Search Result

Gene Information

Gene Name	FANCI
Gene ID	55215
Gene Full Name	FA complementation group I
Gene Alias	KIAA1794
Transcripts	ENSG00000140525
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9NVI1
HGNC ID	HGNC:25568
VEGA ID	OTTHUMG00000132993
OMIM ID	611360
String ID	9606.ENSP00000310842
PharmGKB ID	PA162387928

Target gene [FANCI] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009538	chr15	10	1		11	View
4011448	chr15	3	3	1	7	View
4012899	chr15	2	2		4	View
4013291	chr15	1	2	1	4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FANCI expression and immune infiltrating cell level correlation result in HIV+ samples
FANCI expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FANCI expression and immune infiltrating cell level correlation result in HIV+ samples
FANCI expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).