HBV Target gene Detail Information

> FANCC Gene Search Result


Gene Information
Gene Name FANCC
Gene ID 2176
Gene Full Name FA complementation group C
Gene Alias FA3; FAC; FACC
Transcripts ENSG00000158169
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q00597
HGNC ID HGNC:3584
VEGA ID OTTHUMG00000020279
OMIM ID 613899
String ID 9606.ENSP00000289081
PharmGKB ID PA27997
Target gene [FANCC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011671 chr9 6 2 8 View
1012151 chr9 5 2 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FANCC expression and immune infiltrating cell level correlation result in HBV+ samples
FANCC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).