HIV Target gene Detail Information

> FANCB Gene Search Result


Gene Information
Gene Name FANCB
Gene ID 2187
Gene Full Name FA complementation group B
Gene Alias FA2; FAB; FACB; FAAP90; FAAP95
Transcripts ENSG00000181544
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q8NB91
HGNC ID HGNC:3583
VEGA ID OTTHUMG00000021168
OMIM ID 300515
String ID 9606.ENSP00000381378
PharmGKB ID PA27996
Target gene [FANCB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4016443 chrX 0 View
4016444 chrX 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of FANCB expression and immune infiltrating cell level correlation result in HIV+ samples
FANCB expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of FANCB expression and immune infiltrating cell level correlation result in HIV+ samples
FANCB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).