HIV Target gene Detail Information

> FAM91A1 Gene Search Result

Gene Information

Gene Name	FAM91A1
Gene ID	157769
Gene Full Name	family with sequence similarity 91 member A1
Transcripts	ENSG00000176853
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q658Y4
HGNC ID	HGNC:26306
VEGA ID	OTTHUMG00000133021
String ID	9606.ENSP00000335082
PharmGKB ID	PA142671820

Target gene [FAM91A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007476	chr8	3	16		19	View
4008446	chr8	10	5		15	View
4010355	chr8	5	4		9	View
4012611	chr8	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FAM91A1 expression and immune infiltrating cell level correlation result in HIV+ samples
FAM91A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FAM91A1 expression and immune infiltrating cell level correlation result in HIV+ samples
FAM91A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).