HIV Target gene Detail Information

> FAM76A Gene Search Result


Gene Information
Gene Name FAM76A
Gene ID 199870
Gene Full Name family with sequence similarity 76 member A
Transcripts ENSG00000009780
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8TAV0
HGNC ID HGNC:28530
VEGA ID OTTHUMG00000003729
String ID 9606.ENSP00000010299
PharmGKB ID PA142671837
Target gene [FAM76A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005025 chr1 17 19 36 View
4006316 chr1 7 15 3 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of FAM76A expression and immune infiltrating cell level correlation result in HIV+ samples
FAM76A expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of FAM76A expression and immune infiltrating cell level correlation result in HIV+ samples
FAM76A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).