HPV Target gene Detail Information

> FAM27C Gene Search Result

Gene Information

Gene Name	FAM27C
Gene ID	100132948
Gene Full Name	family with sequence similarity 27 member C
Gene Alias	FAM27A; FAM27A1; FAM27A3; bA7G23.5
Transcripts	ENSG00000231527
Virus	HPV
Gene Type	ncRNA
HPA Location Info
HGNC ID	HGNC:23668
VEGA ID	OTTHUMG00000013240
String ID	9606.ENSP00000366765
PharmGKB ID	PA142671891

Target gene [FAM27C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5404673	chr9	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of FAM27C expression and immune infiltrating cell level correlation result in HPV+ samples
FAM27C expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of FAM27C expression and immune infiltrating cell level correlation result in HPV+ samples
FAM27C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).