HIV Target gene Detail Information

> FAM222B Gene Search Result

Gene Information

Gene Name	FAM222B
Gene ID	55731
Gene Full Name	family with sequence similarity 222 member B
Gene Alias	C17orf63
Transcripts	ENSG00000173065
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WU58
HGNC ID	HGNC:25563
String ID	9606.ENSP00000462419
PharmGKB ID	PA142672246

Target gene [FAM222B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004741	chr17	7	28	5	40	View
4005470	chr17	32			32	View
4010473	chr17	4	5		9	View
4013445	chr17	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FAM222B expression and immune infiltrating cell level correlation result in HIV+ samples
FAM222B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).