HTLV1 Target gene Detail Information

> FAM189B Gene Search Result

Gene Information

Gene Name	FAM189B
Gene ID	10712
Gene Full Name	family with sequence similarity 189 member B
Gene Alias	COTE1; C1orf2
Transcripts	ENSG00000262666
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P81408
HGNC ID	HGNC:1233
VEGA ID	OTTHUMG00000175266
String ID	9606.ENSP00000354958
PharmGKB ID	PA25608

Target gene [FAM189B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003381	chr1	151	12		163	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of FAM189B expression and immune infiltrating cell level correlation result in HTLV1+ samples
FAM189B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).