HBV Target gene Detail Information

> FAM171B Gene Search Result


Gene Information
Gene Name FAM171B
Gene ID 165215
Gene Full Name family with sequence similarity 171 member B
Gene Alias KIAA1946
Transcripts ENSG00000144369
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q6P995
HGNC ID HGNC:29412
VEGA ID OTTHUMG00000154278
String ID 9606.ENSP00000304108
PharmGKB ID PA162387220
Target gene [FAM171B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1400052 chr2 3 4 7 View
1400077 chr2 18 18 View
1400155 chr2 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FAM171B expression and immune infiltrating cell level correlation result in HBV+ samples
FAM171B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).