HBV Target gene Detail Information

> FAM149B1 Gene Search Result


Gene Information
Gene Name FAM149B1
Gene ID 317662
Gene Full Name family with sequence similarity 149 member B1
Gene Alias KIAA0974
Transcripts ENSG00000138286
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96BN6
HGNC ID HGNC:29162
VEGA ID OTTHUMG00000067794
OMIM ID 618413
String ID 9606.ENSP00000242505
PharmGKB ID PA162386399
Target gene [FAM149B1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014016 chr10 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FAM149B1 expression and immune infiltrating cell level correlation result in HBV+ samples
FAM149B1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).