HBV Target gene Detail Information

> FAM135B Gene Search Result

Gene Information

Gene Name	FAM135B
Gene ID	51059
Gene Full Name	family with sequence similarity 135 member B
Gene Alias	C8ORFK32
Transcripts	ENSG00000147724
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q49AJ0
HGNC ID	HGNC:28029
VEGA ID	OTTHUMG00000149864
String ID	9606.ENSP00000378710
PharmGKB ID	PA162386277

Target gene [FAM135B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013193	chr8	5			5	View
1017053	chr8	1			1	View
1019362	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FAM135B expression and immune infiltrating cell level correlation result in HBV+ samples
FAM135B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).