HIV Target gene Detail Information

> FAM126A Gene Search Result

Gene Information

Gene Name	FAM126A
Gene ID	84668
Gene Full Name	family with sequence similarity 126 member A
Gene Alias	HCC; HLD5; HYCC1; DRCTNNB1A
Transcripts	ENSG00000122591
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9BYI3
HGNC ID	HGNC:24587
VEGA ID	OTTHUMG00000128435
OMIM ID	610531
String ID	9606.ENSP00000403396
PharmGKB ID	PA162385852

Target gene [FAM126A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003137	chr7	59	5	5	69	View
4010382	chr7	5	4		9	View
4015140	chr7	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FAM126A expression and immune infiltrating cell level correlation result in HIV+ samples
FAM126A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FAM126A expression and immune infiltrating cell level correlation result in HIV+ samples
FAM126A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).