HIV Target gene Detail Information

> FAM117B Gene Search Result

Gene Information

Gene Name	FAM117B
Gene ID	150864
Gene Full Name	family with sequence similarity 117 member B
Gene Alias	ALS2CR13
Transcripts	ENSG00000138439
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Centrosome;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P1L5
HGNC ID	HGNC:14440
VEGA ID	OTTHUMG00000154550
String ID	9606.ENSP00000376071
PharmGKB ID	PA164719514

Target gene [FAM117B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011235	chr2	5	2		7	View
4011844	chr2	3	3		6	View
4012953	chr2	3	1		4	View
4012954	chr2	3	1		4	View
4015340	chr2		1		1	View
4015657	chr2	1			1	View
4100023	chr2	15	1		16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FAM117B expression and immune infiltrating cell level correlation result in HIV+ samples
FAM117B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FAM117B expression and immune infiltrating cell level correlation result in HIV+ samples
FAM117B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).