HPV Target gene Detail Information

> FAHD2B Gene Search Result

Gene Information

Gene Name	FAHD2B
Gene ID	151313
Gene Full Name	fumarylacetoacetate hydrolase domain containing 2B
Transcripts	ENSG00000144199
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P2I3
HGNC ID	HGNC:25318
VEGA ID	OTTHUMG00000130533
String ID	9606.ENSP00000410470
PharmGKB ID	PA162385597

Target gene [FAHD2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5404134	chr2	669	137	25	831	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of FAHD2B expression and immune infiltrating cell level correlation result in HPV+ samples
FAHD2B expression: Low -> High

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of FAHD2B expression and immune infiltrating cell level correlation result in HPV+ samples
FAHD2B expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of FAHD2B expression and immune infiltrating cell level correlation result in HPV+ samples
FAHD2B expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of FAHD2B expression and immune infiltrating cell level correlation result in HPV+ samples
FAHD2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).