Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Target gene Detail Information

> F8 Gene Search Result


Gene Information
Gene Name F8
Gene ID 2157
Gene Full Name coagulation factor VIII
Gene Alias AHF; F8B; F8C; HEMA; FVIII; DXS1253E
Transcripts ENSG00000185010
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P00451
HGNC ID HGNC:3546
VEGA ID OTTHUMG00000022688
OMIM ID 300841
String ID 9606.ENSP00000353393
Drugbank ID BE0000016
PharmGKB ID PA27952
Target gene [F8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000358 chr16 155 364 1 520 View
4001471 chr19 37 105 18 160 View
4003759 chr6 43 5 7 55 View
4004427 chr6 37 6 1 44 View
4004768 chrX 34 5 39 View
4005427 chr9 33 33 View
4005597 chr10 16 7 8 31 View
4006561 chr1 21 3 24 View
4007598 chr1 18 18 View
4008505 chr6 10 2 3 15 View
4008952 chr19 12 1 13 View
4011581 chr16 4 1 1 6 View
4011629 chr6 5 1 6 View
4011817 chrX 5 1 6 View
4012676 chr1 4 4 View
4014524 chr6 1 1 2 View
4014525 chr6 2 2 View
4016692 chrX 0 View
4100005 chr6 1 1 View
4100036 chr9 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of F8 expression and immune infiltrating cell level correlation result in HIV+ samples
F8 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of F8 expression and immune infiltrating cell level correlation result in HIV+ samples
F8 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).