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HBV Target gene Detail Information

> F10 Gene Search Result


Gene Information
Gene Name F10
Gene ID 2159
Gene Full Name coagulation factor X
Gene Alias FX; FXA
Transcripts ENSG00000126218
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID P00742
HGNC ID HGNC:3528
VEGA ID OTTHUMG00000017374
OMIM ID 613872
String ID 9606.ENSP00000364709
Drugbank ID BE0000216
PharmGKB ID PA27940
Target gene [F10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008278 chr12 6 12 3 21 View
1009495 chr12 6 7 2 15 View
1010767 chr13 11 11 View
1013163 chr8 1 3 1 5 View
1016275 chr5 1 1 View
1017064 chr3 1 1 View
1017110 chr5 1 1 View
1400181 chr13 5 9 2 16 View
1403388 chr12 6 12 3 21 View
1403389 chr12 6 7 2 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of F10 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
F10 expression: Low -> High
Lollipop of F10 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of F10 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of F10 expression and immune infiltrating cell level correlation result in HBV+ samples
F10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).