HIV Target gene Detail Information

> EZH1 Gene Search Result


Gene Information
Gene Name EZH1
Gene ID 2145
Gene Full Name enhancer of zeste 1 polycomb repressive complex 2 subunit
Gene Alias KMT6B
Transcripts ENSG00000108799
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q92800
HGNC ID HGNC:3526
VEGA ID OTTHUMG00000180645
OMIM ID 601674
String ID 9606.ENSP00000404658
Drugbank ID BE0010093; BE0009849
PharmGKB ID PA27938
Target gene [EZH1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006232 chr17 20 6 26 View
4014712 chr17 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of EZH1 expression and immune infiltrating cell level correlation result in HIV+ samples
EZH1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).