Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> EXTL3 Gene Search Result


Gene Information
Gene Name EXTL3
Gene ID 2137
Gene Full Name exostosin like glycosyltransferase 3
Gene Alias RPR; BOTV; REGR; EXTR1; ISDNA; EXTL1L
Transcripts ENSG00000012232
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID O43909
HGNC ID HGNC:3518
VEGA ID OTTHUMG00000102146
OMIM ID 605744
String ID 9606.ENSP00000220562
PharmGKB ID PA27930
Target gene [EXTL3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016062 chr8 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of EXTL3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
EXTL3 expression: Low -> High
Lollipop of EXTL3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of EXTL3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EXTL3 expression and immune infiltrating cell level correlation result in HBV+ samples
EXTL3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).