HIV Target gene Detail Information

> EXOSC4 Gene Search Result

Gene Information

Gene Name	EXOSC4
Gene ID	54512
Gene Full Name	exosome component 4
Gene Alias	SKI6; p12A; RRP41; Ski6p; RRP41A; Rrp41p; hRrp41p
Transcripts	ENSG00000178896
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9NPD3
HGNC ID	HGNC:18189
VEGA ID	OTTHUMG00000165437
OMIM ID	606491
String ID	9606.ENSP00000315476
PharmGKB ID	PA134867931

Target gene [EXOSC4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009282	chr8	6	4	2	12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EXOSC4 expression and immune infiltrating cell level correlation result in HIV+ samples
EXOSC4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).