HIV Target gene Detail Information

> EXOC2 Gene Search Result

Gene Information

Gene Name	EXOC2
Gene ID	55770
Gene Full Name	exocyst complex component 2
Gene Alias	SEC5; Sec5p; SEC5L1
Transcripts	ENSG00000112685
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, RAS pathway related proteins, Transporters
Uniport_ID	Q96KP1
HGNC ID	HGNC:24968
VEGA ID	OTTHUMG00000137437
OMIM ID	615329
String ID	9606.ENSP00000230449
PharmGKB ID	PA134862170

Target gene [EXOC2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000193	chr6	7	533	226	766	View
4004451	chr6	23	20	1	44	View
4005374	chr6	30	3		33	View
4006559	chr6	19	3	2	24	View
4006706	chr6	1	17	5	23	View
4007160	chr6	14	2	4	20	View
4009760	chr6	1	10		11	View
4009972	chr6	10			10	View
4009973	chr6	10			10	View
4011401	chr6	7			7	View
4011852	chr6	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EXOC2 expression and immune infiltrating cell level correlation result in HIV+ samples
EXOC2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EXOC2 expression and immune infiltrating cell level correlation result in HIV+ samples
EXOC2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).