HTLV1 Target gene Detail Information

> EXD3 Gene Search Result

Gene Information

Gene Name	EXD3
Gene ID	54932
Gene Full Name	exonuclease 3'-5' domain containing 3
Gene Alias	mut-7
Transcripts	ENSG00000187609
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Focal adhesion sites;Actin filaments;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N9H8
HGNC ID	HGNC:26023
VEGA ID	OTTHUMG00000156149
String ID	9606.ENSP00000340474
PharmGKB ID	PA164719422

Target gene [EXD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003954	chr9	115	18	1	134	View
6008378	chr9	4	18	24	46	View
6014670	chr9	14	2		16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of EXD3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EXD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).