HIV Target gene Detail Information

> EVI5 Gene Search Result

Gene Information

Gene Name	EVI5
Gene ID	7813
Gene Full Name	ecotropic viral integration site 5
Gene Alias	NB4S; EVI-5
Transcripts	ENSG00000067208
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	O60447
HGNC ID	HGNC:3501
VEGA ID	OTTHUMG00000010895
OMIM ID	602942
String ID	9606.ENSP00000359356
PharmGKB ID	PA27915

Target gene [EVI5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011544	chr1	3	3		6	View
4013546	chr1	3			3	View
4014662	chr1	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EVI5 expression and immune infiltrating cell level correlation result in HIV+ samples
EVI5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EVI5 expression and immune infiltrating cell level correlation result in HIV+ samples
EVI5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).