HIV Target gene Detail Information

> EVI2B Gene Search Result

Gene Information

Gene Name	EVI2B
Gene ID	2124
Gene Full Name	ecotropic viral integration site 2B
Gene Alias	EVDB; CD361; D17S376
Transcripts	ENSG00000185862
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Focal adhesion sites;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins
Uniport_ID	P34910
HGNC ID	HGNC:3500
VEGA ID	OTTHUMG00000132869
OMIM ID	158381
String ID	9606.ENSP00000333779
PharmGKB ID	PA27914

Target gene [EVI2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004390	chr17	19	17	9	45	View
4005085	chr17	31	5		36	View
4005249	chr17	13	9	12	34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EVI2B expression and immune infiltrating cell level correlation result in HIV+ samples
EVI2B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EVI2B expression and immune infiltrating cell level correlation result in HIV+ samples
EVI2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).