HIV Target gene Detail Information

> ETV6 Gene Search Result

Gene Information

Gene Name	ETV6
Gene ID	2120
Gene Full Name	ETS variant 6
Gene Alias	TEL; THC5; TEL/ABL
Transcripts	ENSG00000139083
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene & Oncogene
Uniport_ID	P41212
HGNC ID	HGNC:3495
VEGA ID	OTTHUMG00000168538
OMIM ID	600618
String ID	9606.ENSP00000379658
PharmGKB ID	PA27909

Target gene [ETV6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003817	chr12	48	4	2	54	View
4007184	chr12	17	2	1	20	View
4009067	chr12	11	2		13	View
4016074	chr12				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ETV6 expression and immune infiltrating cell level correlation result in HIV+ samples
ETV6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ETV6 expression and immune infiltrating cell level correlation result in HIV+ samples
ETV6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).