HIV Target gene Detail Information

> ETS1 Gene Search Result

Gene Information

Gene Name	ETS1
Gene ID	2113
Gene Full Name	ETS proto-oncogene 1, transcription factor
Gene Alias	p54; ETS-1; EWSR2; c-ets-1
Transcripts	ENSG00000134954
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P14921
HGNC ID	HGNC:3488
VEGA ID	OTTHUMG00000165799
OMIM ID	164720
String ID	9606.ENSP00000376436
PharmGKB ID	PA27902

Target gene [ETS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001424	chr11	54	104	9	167	View
4004909	chr11	18	19	1	38	View
4005626	chr11	2	27	2	31	View
4005627	chr11	2	27	2	31	View
4005905	chr11	15		13	28	View
4008757	chr11	6	6	2	14	View
4008807	chr11	2	11	1	14	View
4009130	chr11	10	2		12	View
4009897	chr11	2	8		10	View
4012699	chr11		4		4	View
4014676	chr11	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ETS1 expression and immune infiltrating cell level correlation result in HIV+ samples
ETS1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ETS1 expression and immune infiltrating cell level correlation result in HIV+ samples
ETS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).