HIV Target gene Detail Information

> ETNK1 Gene Search Result

Gene Information

Gene Name	ETNK1
Gene ID	55500
Gene Full Name	ethanolamine kinase 1
Gene Alias	EKI; EKI1; EKI 1; Nbla10396
Transcripts	ENSG00000139163
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9HBU6
HGNC ID	HGNC:24649
VEGA ID	OTTHUMG00000169008
OMIM ID	609858
String ID	9606.ENSP00000266517
PharmGKB ID	PA134921265

Target gene [ETNK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008477	chr12	13	2		15	View
4012442	chr12	1	4		5	View
4015241	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ETNK1 expression and immune infiltrating cell level correlation result in HIV+ samples
ETNK1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ETNK1 expression and immune infiltrating cell level correlation result in HIV+ samples
ETNK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).