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HBV Target gene Detail Information

> ETFDH Gene Search Result


Gene Information
Gene Name ETFDH
Gene ID 2110
Gene Full Name electron transfer flavoprotein dehydrogenase
Gene Alias MADD; ETFQO
Transcripts ENSG00000171503
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q16134
HGNC ID HGNC:3483
VEGA ID OTTHUMG00000161684
OMIM ID 231675
String ID 9606.ENSP00000426638
Drugbank ID BE0003887
PharmGKB ID PA27899
Target gene [ETFDH] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005293 chr4 12 27 18 57 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ETFDH expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ETFDH expression: Low -> High
Lollipop of ETFDH expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ETFDH expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ETFDH expression and immune infiltrating cell level correlation result in HBV+ samples
ETFDH expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).