HBV Target gene Detail Information

> ESYT2 Gene Search Result


Gene Information
Gene Name ESYT2
Gene ID 57488
Gene Full Name extended synaptotagmin 2
Gene Alias E-Syt2; FAM62B; CHR2SYT
Transcripts ENSG00000117868
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID A0FGR8
HGNC ID HGNC:22211
VEGA ID OTTHUMG00000151436
OMIM ID 616691
String ID 9606.ENSP00000251527
PharmGKB ID PA165617947
Target gene [ESYT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010376 chr7 2 7 3 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ESYT2 expression and immune infiltrating cell level correlation result in HBV+ samples
ESYT2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).