HBV Target gene Detail Information

> ESRRG Gene Search Result

Gene Information

Gene Name	ESRRG
Gene ID	2104
Gene Full Name	estrogen related receptor gamma
Gene Alias	ERR3; ERRg; NR3B3; ERRgamma; ERR-gamma
Transcripts	ENSG00000196482
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors
Uniport_ID	P62508
HGNC ID	HGNC:3474
VEGA ID	OTTHUMG00000037025
OMIM ID	602969
String ID	9606.ENSP00000355904
Drugbank ID	BE0002088
PharmGKB ID	PA27891

Target gene [ESRRG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007619	chr1	10	13	2	25	View
1008272	chr1	3	14	4	21	View
1015549	chr1	2			2	View
1015952	chr1		2		2	View
1017447	chr1		1		1	View
1019586	chr1				0	View
1400137	chr1	740	85	57	882	View
1403717	chr1	3	14	4	21	View
1403718	chr1	10	13	2	25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ESRRG expression and immune infiltrating cell level correlation result in HBV+ samples
ESRRG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).