HTLV1 Target gene Detail Information

> ESF1 Gene Search Result

Gene Information

Gene Name	ESF1
Gene ID	51575
Gene Full Name	ESF1 nucleolar pre-rRNA processing protein homolog
Gene Alias	ABTAP; C20orf6; HDCMC28P; bA526K24.1
Transcripts	ENSG00000089048
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H501
HGNC ID	HGNC:15898
VEGA ID	OTTHUMG00000031906
OMIM ID	618765
String ID	9606.ENSP00000202816
PharmGKB ID	PA162385420

Target gene [ESF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007141	chr20	56	3		59	View
6013386	chr20	17	2		19	View
6016989	chr20	6	2	3	11	View
6025328	chr12	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ESF1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ESF1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ESF1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ESF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).