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HBV Target gene Detail Information

> ERRFI1 Gene Search Result


Gene Information
Gene Name ERRFI1
Gene ID 54206
Gene Full Name ERBB receptor feedback inhibitor 1
Gene Alias MIG6; RALT; MIG-6; GENE-33
Transcripts ENSG00000116285
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9UJM3
HGNC ID HGNC:18185
VEGA ID OTTHUMG00000001221
OMIM ID 608069
String ID 9606.ENSP00000366702
PharmGKB ID PA142671904
Target gene [ERRFI1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002509 chr1 73 126 61 260 View
1006868 chr1 33 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ERRFI1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ERRFI1 expression: Low -> High
Lollipop of ERRFI1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ERRFI1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ERRFI1 expression and immune infiltrating cell level correlation result in HBV+ samples
ERRFI1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).