HTLV1 Target gene Detail Information

> ERGIC1 Gene Search Result


Gene Information
Gene Name ERGIC1
Gene ID 57222
Gene Full Name endoplasmic reticulum-golgi intermediate compartment 1
Gene Alias AMCN; NET24; ERGIC32; ERGIC-32
Transcripts ENSG00000113719
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Gene Function Oncogene
Uniport_ID Q969X5
HGNC ID HGNC:29205
VEGA ID OTTHUMG00000130520
OMIM ID 617946
String ID 9606.ENSP00000377374
PharmGKB ID PA143485456
Target gene [ERGIC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001060 chr5 463 110 36 609 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ERGIC1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ERGIC1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ERGIC1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ERGIC1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ERGIC1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ERGIC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).