HIV Target gene Detail Information

> ERG Gene Search Result

Gene Information

Gene Name	ERG
Gene ID	2078
Gene Full Name	ETS transcription factor ERG
Gene Alias	p55; erg-3
Transcripts	ENSG00000157554
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P11308
HGNC ID	HGNC:3446
VEGA ID	OTTHUMG00000090767
OMIM ID	165080
String ID	9606.ENSP00000414150
PharmGKB ID	PA27858

Target gene [ERG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013108	chr21	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ERG expression and immune infiltrating cell level correlation result in HIV+ samples
ERG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).