HBV Target gene Detail Information

> ERC1 Gene Search Result

Gene Information

Gene Name	ERC1
Gene ID	23085
Gene Full Name	ELKS/RAB6-interacting/CAST family member 1
Gene Alias	ELKS; Cast2; ERC-1; RAB6IP2
Transcripts	ENSG00000082805
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Vesicles;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID	Q8IUD2
HGNC ID	HGNC:17072
VEGA ID	OTTHUMG00000130138
OMIM ID	607127
String ID	9606.ENSP00000468263
PharmGKB ID	PA134970875

Target gene [ERC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002484	chr12	92	65	112	269	View
1008676	chr12	18	2		20	View
1015426	chr12	1		1	2	View
1019141	chr15				0	View
1400257	chr12	253	12		265	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ERC1 expression and immune infiltrating cell level correlation result in HBV+ samples
ERC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).